From the National Health and Nutrition Examination Survey 2011-2014 (National Center for Health Statistics) and the National Heart, Lung, and Blood Institute.
Percentages for racial/ethnic groups are age-adjusted for US adults ≥ 20 years of age.
The incidence of new cases is for adults ≥ 45 years of age.
The cross-sectional Italian study consisted of 380 patients who underwent coronary angiography— 95 patients with coronary artery disease (CAD) reported having chronic angina.2
Chronic angina was defined as clinical and noninvasive evidence of stable myocardial ischemia lasting >2 months.
All patients underwent angiography for Acute Coronary Syndrome or Chronic CAD at the Institute of Cardiology of the University of Milan. Erectile function was evaluated using the erectile function domain of the International Index of Erectile Function (IIEF-EFD), a validated 15-item self-administered questionnaire. 50.5% (48/49) of patients with chronic angina were taking beta-blockers, although logistic regression analysis showed that beta-blockers did not have significant impact on ED when adjusted for other confounding variables.
1957 patients with coronary artery disease (CAD) were evaluated from the US National Health and Nutrition Examination Survey (NHANES) from 2001 to 2010.¶3
This study was supported by a contract from Gilead Sciences, Inc. to the University of California, Irvine. Drs Calara and Koch are employees of Gilead Sciences, Inc.
Percentages reported in the publication were calculated using population-weighted values. CAD defined by self-report. Diabetes mellitus defined by fasting glucose ≥126 mg/dL, nonfasting glucose ≥200 mg/dL, previous physician diagnosis of DM, or use of insulin or hypoglycemic medication. Angina was determined by either self-report or determined using the Rose Questionnaire for verified class 1 or class 2 angina pectoris.
Is angina under-recognized in your patients? Assessing patient activity levels and the presence or absence of symptoms during patient visits is important in order to accurately estimate your patients’ angina burden.
APPEAR (Angina Prevalence and Provider Evaluation of Angina Relief) is a cross-sectional study of stable CAD patients (N=1257) enrolled 2013-2015 from 25 US cardiology practices participating in the ACC PINNACLE registry. 8% (n=96) reported daily/weekly, 25% (n=315) reported monthly, and 67% (n=846) of patients reported no angina using the Seattle Angina Questionnaire.
PINNACLE (Practice INNovation And CLinical Excellence) is cardiology’s largest outpatient quality improvement registry, with over 3 million patients across 127 US sites. Gilead provided funding for this investigator-initiated study.4,6,7
Under-recognition was defined as the physician reporting a lower frequency of angina than the patient had reported using the Seattle Angina Questionnaire (SAQ) domain.
CAD=coronary artery disease.
Learn more about the prevalence of chronic angina in patients post-PCI.See the data